Status:
TERMINATED
Effects of Standard Treatment of Acute Coronary Syndromes on Macrophage Activity as Measured by Serum Neopterin
Lead Sponsor:
Winthrop University Hospital
Conditions:
Acute Coronary Syndrome
Eligibility:
All Genders
19+ years
Brief Summary
This is a prospective observational study focused on monitoring the effects of various treatment options for acute coronary syndrome (ACS) patients by measuring serum neopterin levels. Serum neopterin...
Detailed Description
The study is a prospective observational study focused on monitoring the effects of various treatment options for acute coronary syndrome (ACS) patients by measuring serum neopterin levels. Serum neop...
Eligibility Criteria
Inclusion
- Chest pain and either ST segment elevation or depression \> 0.1 mV in at least 2 contiguous electrocardiographic leads as well as elevation in troponin levels.
Exclusion
- History of medical conditions known to alter neopterin concentrations in blood. The exclusion criteria includes:
- renal failure,
- history of HIV,
- transplant patients,
- active infections,
- history of autoimmune disease,
- malignancy,
- phenylketonuria,
- immune mediated liver disease, and
- patients taking immunomodulating therapy.
Key Trial Info
Start Date :
July 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT00952055
Start Date
July 1 2003
End Date
August 1 2011
Last Update
January 16 2015
Active Locations (1)
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1
Winthrop-University Hospital
Mineola, New York, United States, 11501