Status:

COMPLETED

Efficacy and Safety of Kunxian Capsule in Treatment Patients With Early Ankylosing Spondylitis

Lead Sponsor:

Gu Jieruo

Collaborating Sponsors:

China-Japan Friendship Hospital

Dongguan People's Hospital

Conditions:

Ankylosing Spondylitis

Treatment

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

This is a prospective randomized controlled study to evaluated the efficacy and safety of kunxian capsule in treating of patients with early ankylosing spondylitis (AS). The major outcome index is pro...

Eligibility Criteria

Inclusion

  • 16 to 65 years old, having signed the informed consent;
  • fulfill the ESSG criteria for diagnosis of SpA; not fulfill the 1984 modified NewYork criteria for AS;
  • BASDAI score more than 4;
  • stop taking DMARDs for at least 4 weeks;
  • NSAIDs dosage has been stable for at least 4 weeks;

Exclusion

  • Intra-articular injection of cortisone within 3 months.
  • History of heart failure, multiple sclerosis, COPD, lymphoma or other tumors;
  • Accompanied by fibromyalgia or other rheumatic diseases;
  • Female of pregnancy or breast feeding;
  • History of mental disease and poor compliance.
  • History of drug abuse or alcoholism.

Key Trial Info

Start Date :

January 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2009

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT00953979

Start Date

January 1 2008

End Date

December 1 2009

Last Update

January 19 2012

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Rheumatology Department, the Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510630

Efficacy and Safety of Kunxian Capsule in Treatment Patients With Early Ankylosing Spondylitis | DecenTrialz