Status:
COMPLETED
Acute Cardiovascular and Metabolic Effects of Exercise Training in Individuals With Insulin Resistance
Lead Sponsor:
US Department of Veterans Affairs
Conditions:
Insulin Resistance
Eligibility:
All Genders
30-65 years
Phase:
NA
Brief Summary
The overall aim of the project is to determine whether or not exercise influences cardiovascular or nervous responses to meal ingestion in individuals with insulin resistance or type 2 diabetes.
Detailed Description
Participants will undergo a screening procedure, including telephone screening and physical examination, as well as determination of body composition and fitness. Participants will be asked to complet...
Eligibility Criteria
Inclusion
- Insulin resistant: diagnosed with pre-diabetes or fasting blood glucose \>/= 100 mg/dL
- T2D: diagnosed by primary care physician
- BMI: less than 43 kg/m2
- Age: 30-65
Exclusion
- Smoking
- Insulin use (other than once daily)
- Underlying conditions that limit ability to exercise safely
- Recent weight gain or loss (\>5% of body weight in 3 months)
- Physically active (\>30 min aerobic exercise, 2 d/wk)
- Recent (\<3 mo) changes in medication use or dose
- Uncontrolled T2D (HbA1c\>10%)
- Advanced retinopathy or neuropathy
- Pregnancy
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT00954109
Start Date
August 1 2009
End Date
December 1 2010
Last Update
April 6 2015
Active Locations (1)
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1
Harry S. Truman Memorial VA Medical Center
Columbia, Missouri, United States, 65201-5297