Status:

TERMINATED

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease

Lead Sponsor:

Medivation, Inc.

Collaborating Sponsors:

Pfizer

Conditions:

Moderate to Severe Alzheimer

Eligibility:

All Genders

50+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine if Dimebon is safe and effective in patients with moderate to severe Alzheimer's disease.

Eligibility Criteria

Inclusion

  • Moderate-to-Severe Alzheimer's disease
  • Mini-Mental State Examination (MMSE) Score between 5 to 14, inclusive
  • Stable on donepezil for at least 6 months

Exclusion

  • Other causes of dementia
  • Major structural brain disease
  • Unstable medical condition or significant hepatic or renal disease

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

89 Patients enrolled

Trial Details

Trial ID

NCT00954590

Start Date

October 1 2009

Last Update

September 27 2016

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Santiago, Chile

2

Glasgow, Scotland, United Kingdom