Status:
WITHDRAWN
Utilization of Diagnostic Ultrasound in the Detection and Therapy of Acute Coronary Syndromes
Lead Sponsor:
University of Nebraska
Collaborating Sponsors:
Microvascular Therapeutics, LLC
The Ruth and Bruce Rappaport Faculty of Medicine
Conditions:
Acute Coronary Syndrome
Myocardial Infarction
Eligibility:
All Genders
30+ years
Phase:
NA
Brief Summary
The study will see if mechanical impulses delivered by an echocardiographic probe during a continuous infusion of MRX 801 are capable of improving blood flow in smaller heart vessels in patients with ...
Detailed Description
Pre-clinical studies have indicated that, during a continuous infusion of intravenous perfluorocarbon-containing microbubbles, the ultrasonic power delivered from a diagnostic ultrasound transducer is...
Eligibility Criteria
Inclusion
- Male or female, age ≥ 30 years.
- Chest Pain occurring lasting less than six hours from onset, and EKG evidence of an acute ST segment elevation myocardial infarction.
- Arrival in the Emergency Department with above inclusion criteria between 7 am and 7pm.
Exclusion
- Known or suspected hypersensitivity to ultrasound contrast agent used for the study.
- Complicated hemodynamic instability (i.e., NYHA Class IV heart failure, unstable angina at rest despite medical therapy).
- Life expectancy of less than two months or terminally ill.
- Heart transplant recipient, hypertrophic cardiomyopathy, severe valvular disease, acute myo- or pericarditis.
- Contraindication to Heart Catheterization
- Known bleeding diathesis or contraindication to glycoprotein 2b/3a inhibitors or aspirin.
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 25 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00955136
Start Date
July 1 2009
End Date
January 25 2010
Last Update
August 14 2023
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