Status:
COMPLETED
Screening and Evaluation of Patients With Signs and Symptoms of Alzheimer's Disease
Lead Sponsor:
National Institute of Mental Health (NIMH)
Conditions:
Alzheimer's Disease
Eligibility:
All Genders
45+ years
Brief Summary
Background: * Individuals who demonstrate symptoms of Alzheimer s disease, such as progressive memory loss, may be eligible to participate in National Institutes of Health research studies. However, ...
Detailed Description
Objective: To provide a mechanism for recruitment and screening of AD patients for inclusion into studies conducted at the National Institutes of Health. To provide data from MRI and \[18F\]FDG and PI...
Eligibility Criteria
Inclusion
- Patients with signs and symptoms of Alzheimer s disease will be recruited from neurological and psychiatric clinics, from self or family referral in response to advertisements or from private physicians. Healthy volunteers will be recruited by the MIB.
- INCLUSION CRITERIA:
- Patients and healthy volunteers must be age 45 or older.
- Patients must have a history of progressive memory impairment.
- Patients must have a caregiver who is willing to accompany the subject to the NIH.
- EXCLUSION CRITERIA FOR PATIENTS:
- The diagnosis of a different type of dementia, including frontotemporal dementia, normal pressure hydrocephalus, Lewy body dementia, Parkinson s disease dementia, Huntington s disease, or vascular dementia.
- Pregnant women. Women of childbearing potential will be screened by history for the possibility of pregnancy and undergo a urine pregnancy test.
- Any medical contraindication to the procedures performed in the study, or any current severe medical or psychiatric illness other than Alzheimer s disease.
- Behavioral symptoms that would preclude the gathering of data for the study, or advanced disease such that subjects cannot provide assent.
- EXCLUSION CRITERIA FOR CONTROLS:
- The diagnosis of a brain disorder.
- Pregnant women.
- Any medical contraindication to the procedures performed in the study, or any current severe medical or psychiatric illness.
Exclusion
Key Trial Info
Start Date :
July 31 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 6 2017
Estimated Enrollment :
197 Patients enrolled
Trial Details
Trial ID
NCT00955422
Start Date
July 31 2009
End Date
July 6 2017
Last Update
July 5 2018
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892