Status:

UNKNOWN

Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Ocular Histoplasmosis Syndrome

Lead Sponsor:

Retina Associates of Kentucky

Collaborating Sponsors:

Genentech, Inc.

Conditions:

Ocular Histoplasmosis Syndrome

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of intravitreal ranibizumab (Lucentis) in patients with fluid and blood leakage in their eyes due to ocular histoplasmosis.

Detailed Description

Patients will be evaluated monthly for one year. Participants will be assigned to one of two groups: Group A will receive 3 monthly injections of ranibizumab followed by an as needed injection throu...

Eligibility Criteria

Inclusion

  • age 18 or over
  • active choroidal neovascularization secondary to ocular histoplasmosis
  • Visual acuity between 20/25 and 20/400

Exclusion

  • pregnancy or intent to become pregnant within the next 12 months
  • nursing an infant
  • premenopausal women not using contraception
  • prior treatment with subfoveal thermal laser
  • allergy to sodium fluorescein simultaneous participation in another investigation or trial

Key Trial Info

Start Date :

August 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00955630

Start Date

August 1 2009

Last Update

August 10 2009

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Retina Associates of Kentucky

Lexington, Kentucky, United States, 40509