Status:
WITHDRAWN
N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Media
Lead Sponsor:
St. Paul's Hospital, Canada
Conditions:
Otitis Media
Otorrhea
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Chronic suppurative otitis media (CSOM) can be particularly difficult to treat as a number of patients do not respond to routine antibiotic or surgical treatments. The current treatment involves admin...
Detailed Description
Chronic suppurative otitis media (CSOM) is the presence of symptoms, signs, and physical findings that can result in long-term damage to the middle ear as a result of infection or inflammation. The co...
Eligibility Criteria
Inclusion
- continuous otorrhea for a duration of greater than 6 months
- at least 2 previous treatment regimes for otitis media, which may include topical or oral antibiotics, myringotomy or tympanostomy, and surgery
Exclusion
- existing cholesteatoma
- known allergy to ciprofloxacin, dexamethasone, or N-acetylcysteine
- patients who are unlikely to adhere to the treatment regime and follow-up visits
Key Trial Info
Start Date :
November 29 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 29 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00956748
Start Date
November 29 2019
End Date
November 29 2019
Last Update
December 3 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
St. Paul's Hospital BC Rotary Hearing & Balance Centre
Vancouver, British Columbia, Canada, V6Z 1Y6