Status:
COMPLETED
Effects of Obstructive Sleep Apnea and/or Cigarette Smoking on Endothelial Function
Lead Sponsor:
The University of Hong Kong
Conditions:
Obstructive Sleep Apnea
Smoking
Eligibility:
All Genders
18+ years
Brief Summary
The hypothesis of this study is that either obstructive sleep apnea (OSA) or cigarette smoking (CS) exposure would produce oxidative stress and inflammation leading to endothelial injury, and the comb...
Eligibility Criteria
Inclusion
- No acute illness
- No hospitalization in past 4 weeks
- Absence of medical comorbidity such as hypertension, ischemic heart disease, diabetes and hyperlipidemia, renal impairment, vasculitis or Raynaud's syndrome, peripheral vascular disease especially Buerger's disease, aortic disease (aortic aneurysm or dilatation), cancer, thrombocytopenia, coagulation disorder or other chronic medical illness
Exclusion
- Mentally incapacitated
Key Trial Info
Start Date :
June 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00957463
Start Date
June 1 2008
Last Update
December 30 2014
Active Locations (1)
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1
Queen Mary Hospital
Hong Kong, Hong Kong, 852