Status:

COMPLETED

Study of Specimens From Young Patients With Neuroblastoma

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Localized Resectable Neuroblastoma

Localized Unresectable Neuroblastoma

Eligibility:

All Genders

Up to 18 years

Brief Summary

This research trial studies specimens from young patients with neuroblastoma. Studying the genes expressed in specimens from patients with cancer may help doctors identify biomarkers related to cancer...

Detailed Description

PRIMARY OBJECTIVES: I. Establish a robust messenger ribonucleic acid (mRNA) gene expression classifier for improved outcome prediction in children with neuroblastoma by using real-time polymerase cha...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Diagnosis of primary Neuroblastoma
  • Untreated disease
  • RNA samples from primary untreated NB-tumors available in Children's Oncology Group (COG) repository
  • At least 60% tumor cells
  • At least 2 years of follow-up from the date of diagnosis
  • Full clinical and biological annotation

Exclusion

    Key Trial Info

    Start Date :

    December 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    May 1 2016

    Estimated Enrollment :

    350 Patients enrolled

    Trial Details

    Trial ID

    NCT00958659

    Start Date

    December 1 2008

    End Date

    May 1 2016

    Last Update

    May 18 2016

    Active Locations (1)

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    Children's Oncology Group

    Philadelphia, Pennsylvania, United States, 19104