Status:

TERMINATED

Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Pancreatic Neoplasm

Pituitary Neoplasm

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This study will assess the effectiveness and safety of pasireotide long-acting release in patients who have rare tumors of neuroendocrine origin.

Eligibility Criteria

Inclusion

  • Male and Female Patients at least 18 years old
  • Patient who have rare tumors of neuroendocrine origin, such as tumors of the:
  • pancreas
  • pituitary glands
  • Nelson syndrome
  • ectopic-ACTH secreting tumor
  • Patients who have failed standard of care treatment or for whom no standard of care treatment exist
  • Signed Informed Consent

Exclusion

  • Patients with active gallbladder disease
  • Patients with any ongoing or planned anti-neoplastic or interferon therapy
  • Poorly controlled diabetes mellitus
  • Female patients who are pregnant or lactating, or are of childbearing potential and not practicing a medically acceptable method of birth control
  • Other protocol-defined inclusion/exclusion criteria may apply.

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2015

Estimated Enrollment :

118 Patients enrolled

Trial Details

Trial ID

NCT00958841

Start Date

September 1 2009

End Date

June 1 2015

Last Update

July 26 2016

Active Locations (42)

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Page 1 of 11 (42 locations)

1

Cedars Sinai Medical Center Cedars Sinai 4

Los Angeles, California, United States, 90048

2

Cedars Sinai Medical Center The Pituitary Center (3)

Los Angeles, California, United States, 90048

3

Stanford University Medical Center SC

Stanford, California, United States, 94304

4

Dana Farber Cancer Institute Deptof DanaFarberCancerInst(5)

Boston, Massachusetts, United States, 02215