Status:

TERMINATED

A Multi Focal Visual Outcome Study Using Different Near Additions

Lead Sponsor:

Rayner Intraocular Lenses Limited

Conditions:

Cataract

Aphakia

Eligibility:

All Genders

18+ years

Brief Summary

A multi-centre non-randomized clinical investigation to assess multifocal visual outcomes using different near additions, for the treatment of aphakia after cataract removal.

Eligibility Criteria

Inclusion

  • Age-related cataract patients undergoing cataract surgery where the cataractous lens has been removed by phacoemulsification, with circular tear capsulotomy, leaving the posterior capsule intact
  • Patients requiring primary IOL implantation
  • Patients with a potential corrected visual acuity of 20/40 or better on clinical assessment
  • Patients with normal anterior segments - apart from cataracts
  • Subjects with clear intraocular media other than cataract

Exclusion

  • Pre-existing pathology or physiology, which may be aggravated by the implant, or may render the implant ineffective and that could potentially cause future acuity losses to a level of 0.5 or 20/40 or worse in either eye. This includes the following:
  • Microphthalmia
  • Corneal decompensation or Endothelial Insufficiency
  • Pseudo exfoliation
  • High myopia
  • Pars planitis
  • Patient with greater than 1 dioptre of pre-operative corneal astigmatism
  • Subjects who are expected to require retinal laser treatment
  • Previous intraocular and/or corneal surgery
  • History of uveitis, glaucoma, proliferative diabetic retinopathy or IDDM, pseudoexfoliation, macular degeneration that may affect potential best corrected visual acuity of 20/40 or better
  • Operative complications of posterior capsular rupture, zonular dehiscence, incomplete continuous curvilinear capsulorhexis, severe iris /corneal trauma and inability to achieve secure placement in the designated location
  • Subjects using a systemic medication that is known to cause ocular side effects
  • Subjects participating in a concurrent clinical trial or if they have participated in an ophthalmology clinical trial within the last 30 days
  • Subjects who have only one eye with potentially good vision
  • Patients who are not willing to cooperate in the 6-months follow-up period
  • Children under the age of 18 years

Key Trial Info

Start Date :

September 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

52 Patients enrolled

Trial Details

Trial ID

NCT00960700

Start Date

September 1 2009

End Date

August 1 2011

Last Update

February 8 2013

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Ruprecht- Karl Universitat Heidelberg

Abteilung Augenheilkunde, Heidelberg, Germany, 69120

2

Eye Clinic and national Centre of Ophthalmology

Kaunas, Lithuania, LT-44307