Status:
COMPLETED
Relationship Between Dopamine Genetics, Food Reinforcement, Energy Intake and Obesity
Lead Sponsor:
State University of New York at Buffalo
Conditions:
Obesity
Eligibility:
All Genders
18-50 years
Brief Summary
The purpose of the study is to determine whether the presentation of various foods produces an increase or decrease in responses on a motivational computer task. In addition, the study determines if e...
Detailed Description
One of the most important research areas in obesity is developing a better understanding of individual differences in factors that influence excess energy intake and positive energy balance. One key t...
Eligibility Criteria
Inclusion
- Non-smokers
- 18-50 years of age
- No known eating disorder
- Moderate liking for study foods
- No current diagnosis of psychiatric disorder (e.g., anxiety or depression)
- Not on medications that would interfere with appetite (e.g., methylphenidate) or dopaminergic activity
- Non-diabetics
Exclusion
- Smoker
- Pregnant women
- Current diagnosis of a psychiatric or eating disorder
- Dietary restrictions that would interfere with participation
- On medications that could interfere with appetite or olfactory responsiveness or use of antidepressants or any medication or dietary supplement that could affect appetite or dopaminergic activity
- Excessive use of alcohol (\>21 drinks/week), alcoholism,current addiction to opiates, cocaine or stimulants
Key Trial Info
Start Date :
February 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
310 Patients enrolled
Trial Details
Trial ID
NCT00962117
Start Date
February 1 2008
End Date
June 1 2011
Last Update
June 13 2012
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