Status:

COMPLETED

Hypopituitarism After Aneurismal Subarachnoid Hemorrhage

Lead Sponsor:

Universitätsmedizin Mannheim

Conditions:

Aneurismal Subarachnoid Hemorrhage

Hypopituitarism

Eligibility:

All Genders

18-85 years

Brief Summary

Introduction: Almost 50% of patients die after aneurismal subarachnoid hemorrhage (aSAH). 30% of the survivors suffer from neurological handicap and need permanent care (Suarez et al.). Even when neu...

Eligibility Criteria

Inclusion

  • aSAH grade I-IV Hunt und Hess
  • bleeding CCT Fisher grade 3-4
  • therapy within 48h after aSAH
  • preoperative angiography as well as control angiography
  • Glasgow Outcome Scale 4 to 5 after therapy

Exclusion

  • known intra-, peri- or suprasellar neoplasia
  • preexisting hypopituitarism of any degree
  • previous hormonal substitution
  • previous radiation
  • for the neuropsychological examination: difficulties with German language

Key Trial Info

Start Date :

February 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2010

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT00962559

Start Date

February 1 2008

End Date

February 1 2010

Last Update

February 17 2010

Active Locations (1)

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Universitätsmedizin Mannheim

Mannheim, Baden-Wurttemberg, Germany, 68169