Status:
WITHDRAWN
Breathing Device for Orthostatic Hypotension (OH)
Lead Sponsor:
Alfredo Gamboa
Collaborating Sponsors:
Vanderbilt University Medical Center
Conditions:
Orthostatic Hypotension
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The investigators will test whether breathing through an inspiratory resistance device will improve the ability to be upright and decrease blood pressure drops on standing in patients with orthostatic...
Detailed Description
Orthostatic hypotension is commonly described, especially in an elderly population. Using data from a national hospital inpatient database, Shibao et al. have reported that the annual hospitalization ...
Eligibility Criteria
Inclusion
- Diagnosed with neurogenic orthostatic hypotension by the Vanderbilt Autonomic Dysfunction Center
- Decrease in systolic blood pressure ≥ 20 mmHg with position change from supine to standing (10 minutes)
- Evidence of reproducibility suggestive of non-reversible nervous system origin for the orthostatic hypotension
- Age between 18-80 years
- Male and female subjects are eligible
- Able and willing to provide informed consent
Exclusion
- Overt cause for orthostatic hypotension (such as acute dehydration)
- Inability to give, or withdrawal of, informed consent
- Pregnant
- Other factors which in the investigator's opinion would prevent the subject from completing the protocol
Key Trial Info
Start Date :
December 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2022
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00962884
Start Date
December 1 2010
End Date
December 1 2022
Last Update
November 22 2021
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232-2195