Status:
COMPLETED
The Renin-Aldosterone Axis in Postural Tachycardia Syndrome
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Postural Orthostatic Tachycardia Syndrome (POTS)
Eligibility:
All Genders
18-64 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine the role of the renin-angiotensin-aldosterone in the pathophysiology of postural tachycardia syndrome, and to provide an insight about the disease process in ...
Eligibility Criteria
Inclusion
- Diagnosis of postural tachycardia syndrome by the Vanderbilt Autonomic Dysfunction Center criteria
- Age between 18-64 years
- Male or females are eligible
- Able and willing to provide informed consent
- Healthy control subjects with no major medical problem (including postural tachycardia syndrome), free of medications during the study
Exclusion
- Overt cause of postural tachycardia e.g., dehydration
- Inability to give or withdraw informed consent
- Pregnancy
- Hypertension (BP \> 140/90)
- Significant co-morbid condition
- Other factors which in the investigator's opinion would prevent the subject from completing the protocol
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT00962949
Start Date
April 1 2009
End Date
December 1 2012
Last Update
September 16 2025
Active Locations (1)
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1
Vanderbilt University
Nashville, Tennessee, United States, 37232