Status:

COMPLETED

Non-invasive Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Blood-Oxygen-Level Dependent Magnetic Resonance Imaging (BOLD MRI)

Lead Sponsor:

University Health Network, Toronto

Conditions:

Hepatocellular Carcinoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Liver resection and liver transplantation are the acceptable treatment of Hepatocellular Carcinoma (HCC). But the long-term survival is unsatisfactory as a result of high rate of intra and extra hepat...

Eligibility Criteria

Inclusion

  • Patients with known Hepatocellular Carcinoma;
  • Scheduled to undergo liver resection or liver transplantation.

Exclusion

  • Estimated GFR (eGFR \< 30 mL/min;
  • MRI contrast allergy;
  • General contraindications to MRI such as pacemaker, etc.;
  • Prior tumor treatment such as transarterial chemoembolization or the tumor or radiofrequency ablation or chemoradiation;
  • Pregnancy;
  • Age less than 18 years.

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00963612

Start Date

September 1 2009

End Date

December 1 2016

Last Update

October 2 2017

Active Locations (1)

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1

University Health Network

Toronto, Ontario, Canada, M5G 2M9