Status:
COMPLETED
The Comparison of Oxidative Stress Between Inhalation Anesthetics
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Oxidative Stress
Cardiac Surgery
Eligibility:
All Genders
25-80 years
Brief Summary
Oxidative stress is an unavoidable event during cardiac surgery. Isoprostanes have been demonstrated to be a reliable biomarker for the evaluation of oxidative stress in vivo.The aims of this study ar...
Detailed Description
Enhanced production of oxygen free radicals can lead to the generation of oxidative stress, which is harmful to human tissue and organs. Reactive oxygen species are released abruptly during some surgi...
Eligibility Criteria
Inclusion
- patients receiving cardiac valve surgery in ASA II-III physical status
Exclusion
- trauma, infection, low ejection fraction (less than 25%), liver cirrhosis, or acute renal failure, and emergency surgery
Key Trial Info
Start Date :
March 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00965445
Start Date
March 1 2007
End Date
December 1 2007
Last Update
August 26 2009
Active Locations (1)
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1
Dept. of Anesthesiology, Chang Gung Memorial Hospital
Taipei, Taiwan, 105