Status:
COMPLETED
Metformin Compared to Glyburide in Gestational Diabetes
Lead Sponsor:
University of New Mexico
Conditions:
Gestational Diabetes
Eligibility:
FEMALE
13+ years
Phase:
NA
Brief Summary
Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.
Detailed Description
Pregnant women are screened with a one hour 50g glucose challenge. Women with values of 130 mg/dl or greater are then given a 100g glucose tolerance test. Two abnormal values are diagnostic of gestati...
Eligibility Criteria
Inclusion
- Gestational diabetes not controlled with diet and exercise
Exclusion
- history of alcohol misuse
- history of drug misuse
- Chronic hypertension requiring medication
- Renal failure
- Hepatic disease or dysfunction
- Known fetal anomaly
- Inability to give consent
- known allergy to metformin or glyburide
Key Trial Info
Start Date :
July 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2023
Estimated Enrollment :
149 Patients enrolled
Trial Details
Trial ID
NCT00965991
Start Date
July 1 2003
End Date
August 1 2023
Last Update
November 19 2024
Active Locations (1)
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1
University of New Mexico Diabetes in Pregnancy Clinic
Albuquerque, New Mexico, United States, 87131