Status:
UNKNOWN
Endoscopic Band Ligation (EBL) Versus Endoscopic Band Ligation and Propranolol for the Prevention of Variceal Rebleeding
Lead Sponsor:
Korea University
Conditions:
Cirrhosis
Variceal Bleeding
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
Both propranolol and endoscopic band ligation (EBL) are effective for prevention of variceal rebleeding. Recently several studies compared the efficacy of EBL alone and with a combination of propranol...
Eligibility Criteria
Inclusion
- liver cirrhosis
- age between 18 and 70 years
- Successful control of esophageal variceal bleeding within 6 weeks before enrollment
Exclusion
- Gastric variceal bleeding
- Patients with systolic blood pressure \<100 mmHg or basal heart rate \<60/min
- Portal vein thrombosis
- Prominent hepatic encephalopathy
- Coexisting untreated malignancy
- Severe cerebrovascular or cardiovascular disease, renal failure
- Previous history of endoscopic, radiologic, or surgical treatment for varices or ascites
- Contraindication to beta-blocker
- Pregnancy
- Refusal to give consent to participate in the trial
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2021
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00966121
Start Date
August 1 2008
End Date
July 1 2021
Last Update
August 23 2017
Active Locations (1)
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1
Korea University Anam Hospital
Seoul, South Korea, 136-705