Status:
COMPLETED
Impact of Chronic Statin Use During Surgery on Inflammation and Infection Rates
Lead Sponsor:
Ottawa Hospital Research Institute
Conditions:
Inflammation
Infection
Eligibility:
All Genders
45+ years
Brief Summary
Despite improvements in perioperative care, non-cardiac surgery remains associated with significant and costly complications. Analysis of perioperative deaths in the United Kingdom suggests that rough...
Detailed Description
It is estimated that approximately 1.7 million surgical procedures are performed each year in Canada. Unfortunately, perioperative complications are not an uncommon occurrence and have substantial mor...
Eligibility Criteria
Inclusion
- over 45 years of age
- able to have a baseline brachial ultrasound test before their day of surgery
- elective high-risk surgery defined by use of the POISE criteria
Exclusion
- lack of informed consent
- pregnant
- contraindication to the brachial artery ultrasound test protocol (i.e. contraindication to 0.4 mg sublingual nitroglycerin)
- enrolled in another conflicting study
- previously enrolled in STAR-VaS or STAR-VaS2
Key Trial Info
Start Date :
November 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2011
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00967252
Start Date
November 1 2008
End Date
July 1 2011
Last Update
July 21 2011
Active Locations (1)
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1
The Ottawa Hospital
Ottawa, Ontario, Canada, K1Y4E9