Status:
COMPLETED
Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
AdventHealth
Conditions:
Pain
Pancreatic Cancer
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
The purpose of this study is to examine endoscopic ultrasound guided celiac plexus neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer as it applies to decreasing t...
Detailed Description
The specific primary aim of this study is to evaluate the efficacy of EUS-CPN + analgesic therapy (Group 1) in pain relief of patients with unresectable pancreatic cancer when compared with analgesic ...
Eligibility Criteria
Inclusion
- Male or Female
- Age ≥19 yrs old
- Abdominal pain typical for pancreatic cancer ≥3/10
- Abdominal CT radiologically consistent with the diagnosis of pancreatic cancer
- Pancreatic cancer confirmed by FNA during EUS
- Inoperability of pancreatic cancer as determined during EUS or prior CT
Exclusion
- Age \< 19 yrs old
- Unable to safely undergo EUS for any reason
- Coagulopathy (prolongation of prothrombin time \> 18 sec, thrombocytopenia \<80,000 platelets/ml)
- Previous CPN or other neurolytic block that could affect pancreatic cancer -related pain or had implanted epidural or intrathecal analgesic therapy
- Another cause for abdominal pain such as pseudocyst, ulcer or other intra-abdominal disorder
- Potential patient noncompliance (refusing to follow schedule of events)
- Active alcohol or other drug use or significant psychiatric illness
- Pregnant or breastfeeding
- Unable to consent
- Non-English speaking
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00968175
Start Date
June 1 2009
End Date
December 1 2013
Last Update
June 4 2014
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
2
Florida Hospital
Orlando, Florida, United States, 32803