Status:
COMPLETED
Olfactory Dysfunction of Rhinosinusitis - Cyclic Adenosine Monophosphate (cAMP)/Calcium Signaling Study
Lead Sponsor:
Greg Davis
Conditions:
Sinusitis
Eligibility:
All Genders
18+ years
Brief Summary
The study examines the biochemistry underlying human olfaction in both normal and diseased states. The study aims are: 1. to determine the levels of cAMP in olfactory tissue from people with chronic ...
Detailed Description
Subject will be recruited from those scheduled to have endoscopic sinus surgery and similar procedures. This study uses the tissue that would normally be discarded during the surgical process. The tis...
Eligibility Criteria
Inclusion
- Subjects will be 18 years old and over and scheduled for one of the following:
- endoscopic sinus surgery for chronic sinusitis
- endoscopic transnasal approach to the pituitary for pituitary tumor removal
- endoscopic inferior turbinectomy or septoplasty for nasal congestion
- endoscopic repair of cerebrospinal fluid (CSF) leaks
Exclusion
- Subjects are excluded if they are unable to give informed consent or unable to complete self-administered questionnaires due to English language barrier, cognitive impairment, or severe medical conditions
Key Trial Info
Start Date :
August 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT00970190
Start Date
August 1 2009
End Date
April 1 2014
Last Update
December 11 2014
Active Locations (1)
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1
University of Washington Medical Center
Seattle, Washington, United States, 98195