Status:
COMPLETED
Oral Contraceptive (OC) Progestin Dose and Breast Proliferation
Lead Sponsor:
University of Southern California
Collaborating Sponsors:
United States Department of Defense
Conditions:
Oral Contraceptive
Eligibility:
FEMALE
18-34 years
Phase:
NA
Brief Summary
The purpose of this research study is to gain a better understanding of the changes that may occur in the breast when a woman uses an oral contraceptive (birth control pill). Some research indicates t...
Eligibility Criteria
Inclusion
- Age 18-34.
- Premenopausal.
- Currently taking or want to start oral contraceptives for contraception
- Non-smoker.
- Competent to give informed consent (as judged by the investigator).
- Provided written informed consent.
- Willingness to refrain from smoking and consumption of grapefruit or grapefruit juice during the study (grapefruit interferes with metabolism of exogenously administered OCs).
Exclusion
- Abnormal breast examination.
- History or current therapeutic or prophylactic use of anticoagulants.
- Known bleeding disorder or history of unexplained bleeding or bruising.
- History of breast cancer or previous diagnostic breast biopsy.
- Known allergy to local anesthetic.
- Currently pregnant or pregnant within the previous 6 months.
- Having any standard contra-indication to being prescribed OCs.
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2008
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT00972439
Start Date
August 1 2007
End Date
November 1 2008
Last Update
February 23 2018
Active Locations (1)
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1
Los Angeles County Hospital
Los Angeles, California, United States, 90033