Status:
COMPLETED
Gabapentin Treatment of Cannabis Dependence
Lead Sponsor:
The Scripps Research Institute
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Cannabis Dependence
Cannabis Withdrawal
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
This is a clinical study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.
Detailed Description
This is a 12-week, double blind, placebo controlled study to evaluate the efficacy of gabapentin in treating outpatients with cannabis dependence. After an initial phone screen, a comprehensive screen...
Eligibility Criteria
Inclusion
- Males or females from 18-65 years of age
- Meets DSM IV criteria for current cannabis dependence
- Seeking research-based outpatient treatment for cannabis dependence that involves daily medication
- Smoked MJ daily at least 25 days per month during the 90 days prior to randomization
- At least a 2-year history of regular MJ use
Exclusion
- Abstinent from cannabis more than 2 days at the time of randomization
- Active suicidal ideation
- Currently meets DSM IV criteria for abuse or dependence on other substances, or has urine drug screen positive for substances, other than cannabis or nicotine
- Significant medical disorders that will increase potential risk or interfere with study participation,
- Sexually active female participants with childbearing potential who are pregnant, nursing or refuse to use a reliable method of birth control
- Meets DSM IV criteria for a major AXIS I disorder other than cannabis and nicotine dependence,
- Inability to understand and/or comply with the provisions of the protocol and consent form
- Treatment with an investigational drug during the previous month
- Sensitivity to study drug as evidenced by adverse drug experiences with gabapentin or its ingredients
- Ongoing treatment with medications that may affect study outcomes
Key Trial Info
Start Date :
November 4 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 19 2016
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00974376
Start Date
November 4 2009
End Date
May 19 2016
Last Update
June 6 2017
Active Locations (1)
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1
The Scripps Research Institute
La Jolla, California, United States, 92037