Status:
COMPLETED
A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Type 2 Diabetes
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
This study will determine the effect of concomitant administration of sitagliptin and metformin on post-meal incretin hormone concentrations in healthy adults.
Eligibility Criteria
Inclusion
- Subject is in good health
- Subject has been a nonsmoker for at least 6 months
- Subject is willing to avoid strenuous activity from the screening visit until the end of the study
- Subject agrees not to consume grapefruit products during the study and to avoid all fruit juices 24 hours before and after study drug administration
Exclusion
- Any history of stroke or neurological disorder
- Subject has a history of cardiovascular, blood, endocrine or liver diseases
- Subject has a history of cancer
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2006
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00975052
Start Date
January 1 2006
End Date
March 1 2006
Last Update
August 19 2015
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