Status:
COMPLETED
Diastolic Dysfunction in Aortic Regurgitation
Lead Sponsor:
University of Bern
Collaborating Sponsors:
Swiss National Science Foundation
Conditions:
Aortic Regurgitation
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Follow-up study in patients with severe aortic regurgitation after successful valve replacement. Systolic and diastolic function were assessed and persistent diastolic dysfunction was observed late (7...
Detailed Description
Background Patients with severe aortic regurgitation show eccentric LV hypertrophy and structural changes of the myocardium. Reversibility of functional and structural changes after successful valve ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Severe aortic regurgitation
- Successful valve replacement
- Informed consent
- Sinus rhythm
- No comorbidities
- No bundle branch block
- No pregnancy
- Exclusion Criteria
- Unwillingness to undergo postop. cath
- diabetes mellitus
- arterial hypertension
- bleeding disorder
- pulmonary hypertension
Exclusion
Key Trial Info
Start Date :
January 1 1996
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT00976625
Start Date
January 1 1996
End Date
December 1 2007
Last Update
September 14 2009
Active Locations (1)
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1
Division of Cardiology
Zurich, Canton of Zurich, Switzerland, 8091