Status:

COMPLETED

Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease

Lead Sponsor:

Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives

Conditions:

Crohn Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

To show the superiority of Azathioprine comparing Mesalazine in the prevention of postoperative recurrence in Crohn's Disease.

Eligibility Criteria

Inclusion

  • more than 18 years old
  • Clinical remission at inclusion time (CDAI\<150)
  • Having ileocolonic or colon resection 21 days before inclusion
  • Resection \> 50cm or subtotal colectomy with ileorectal anastomosis

Exclusion

  • Intolerance to one of both study treatment
  • Liver failure (TP\<60%)
  • Renal Failure (Creatinine \< Lab results)

Key Trial Info

Start Date :

October 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

83 Patients enrolled

Trial Details

Trial ID

NCT00976690

Start Date

October 1 2002

End Date

December 1 2010

Last Update

August 31 2011

Active Locations (14)

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Page 1 of 4 (14 locations)

1

Chu Amiens

Amiens, France, 80054

2

Chu Besancon

Besançon, France, 25030

3

CHU CAEN

Caen, France, 14033

4

Hopital Beaujon

Clichy, France, 92110