Status:

TERMINATED

A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancer

Lead Sponsor:

Pfizer

Conditions:

Small Cell Lung Carcinoma

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This study will summarize the safety of patients receiving figitumumab combined with etoposide and cisplatin (or carboplatin) vs. patients receiving etoposide and cisplatin (or carboplatin) alone as f...

Detailed Description

The study prematurely discontinued on January 26, 2011 due to slow enrollment. It should be noted that safety concerns have not been seen in this study and have not factored into this decision.

Eligibility Criteria

Inclusion

  • Histologically confirmed diagnosis of extensive stage disease Small Cell Lung Cancer (SCLC), with tumor biopsy sample required.
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1. Total IGF-1 \> or = 120 ng/ml

Exclusion

  • Any prior systemic therapy for Small Cell Lung Cancer (SCLC)
  • HbA1c \> or = 5.7%

Key Trial Info

Start Date :

April 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2011

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT00977561

Start Date

April 1 2010

End Date

October 1 2011

Last Update

February 25 2013

Active Locations (51)

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Page 1 of 13 (51 locations)

1

Pfizer Investigational Site

Washington D.C., District of Columbia, United States, 20007-2197

2

Pfizer Investigational Site

Washington D.C., District of Columbia, United States, 20007

3

Pfizer Investigational Site

Marrero, Louisiana, United States, 70072

4

Pfizer Investigational Site

Metairie, Louisiana, United States, 70006