Status:

COMPLETED

Study of Blood and Tissue Samples From Patients With Aggressive Non-Hodgkin B-Cell Lymphoma or Hodgkin Lymphoma

Lead Sponsor:

AIDS Malignancy Consortium

Collaborating Sponsors:

National Cancer Institute (NCI)

The Emmes Company, LLC

Conditions:

Lymphoma

Nonneoplastic Condition

Eligibility:

All Genders

18+ years

Brief Summary

RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURP...

Detailed Description

OBJECTIVES: Primary * To estimate the proportion of patients with diffuse large B-cell/immunoblastic and Burkitt histologies with elevated serum free light chains (FLC). * To estimate the proportion...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of an untreated aggressive B-cell lymphoma, including:
  • Diffuse large B cell/immunoblastic lymphoma
  • Burkitt lymphoma
  • Hodgkin lymphoma
  • Serological documentation of HIV infection by any of the FDA-approved tests
  • Available diagnostic material from fresh frozen tissue or formalin-fixed paraffin embedded tissue OR willing to undergo a repeat biopsy (fine needle aspiration is acceptable)
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    August 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    June 1 2013

    Estimated Enrollment :

    52 Patients enrolled

    Trial Details

    Trial ID

    NCT00981097

    Start Date

    August 1 2009

    End Date

    June 1 2013

    Last Update

    August 7 2020

    Active Locations (16)

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    Page 1 of 4 (16 locations)

    1

    Rebecca and John Moores UCSD Cancer Center

    La Jolla, California, United States, 92093-0658

    2

    UCLA Clinical AIDS Research and Education (CARE) Center

    Los Angeles, California, United States, 90024

    3

    University of California at Davis Center for Aids Research and Education Services

    Sacramento, California, United States, 95814

    4

    UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, United States, 94115