Status:
COMPLETED
Glucose Homeostasis Pre and Post Bariatric Surgery
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
Ethicon Endo-Surgery
Conditions:
Morbid Obesity
Eligibility:
All Genders
20-70 years
Brief Summary
The investigators wish to study the effects of three forms of bariatric surgery: Roux-en-Y gastric bypass, Sleeve Gastrectomy, and Gastric Banding. The surgery is not part of the clinical trial. If yo...
Detailed Description
Bariatric surgery is the most effective weight loss therapy for obesity. Moreover, the early improvement in insulin sensitivity and the resolution of type 2 diabetes after bariatric surgery has led to...
Eligibility Criteria
Inclusion
- BMI ≥ 35 kg/m²
- on stable dose of medications for at least 4 weeks before the pre-surgery metabolic studies
Exclusion
- smokes \> 7 cigarettes per day
- previous malabsorptive or restrictive intestinal surgery
- pregnant or breastfeeding
- recent history of neoplasia (\< 5 years ago)
- have malabsorptive syndromes and inflammatory intestinal disease
- diabetes mellitus
- show signs of oral disease or xerostomia (i.e., dry mouth)
- history of chronic rhinitis
- on medication that might affect metabolism
- severe organ dysfunction
Key Trial Info
Start Date :
December 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00981500
Start Date
December 1 2009
End Date
June 1 2018
Last Update
August 10 2018
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110