Status:

COMPLETED

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Lead Sponsor:

Pfizer

Conditions:

Healthy

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to investigate safety, tolerability and pharmacokinetics of sitaxentan following single and multiple oral administrations of sitaxentan sodium in Japanese healthy subjects...

Eligibility Criteria

Inclusion

  • Healthy male and/or female subjects between the age of 18 and 55 years, inclusive.
  • Body Mass Index of 17.5 to 33.5 kg/m2, and a total body weight \>45 kg. Mean body weight and the body weight range of Western subjects are similar to those of Japanese subjects with a 10% plus and minus error.

Exclusion

  • Pregnant or nursing females; females of childbearing potential who are unwilling or unable to use an acceptable method of contraception.

Key Trial Info

Start Date :

September 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2009

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT00981968

Start Date

September 1 2009

End Date

November 1 2009

Last Update

October 15 2010

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Pfizer Investigational Site

Glendale, California, United States, 91206