Status:
UNKNOWN
Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate.
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Asthma
Cystic Fibrosis
Eligibility:
All Genders
6-18 years
Brief Summary
Background: in various pediatric pulmonary diseases such as asthma, cystic fibrosis or bronchopulmonary dysplasia an increased inflammation is present. Measuring this inflammation is often hardly poss...
Detailed Description
Background of the study: Measurement of inflammatory markers (IM) in exhaled breath and exhaled breath condensate (EB(C)) is a very interesting and useful non-invasive new technique to evaluate airwa...
Eligibility Criteria
Inclusion
- study part I and II:
- healthy adults, 18-50 years study part III:
- healthy children age 6-18 years
- patients with cystic fibrosis
- patients with asthma
- patients with chronic lung disease
- patients with pneumonia, all age 6-18 years
Exclusion
- Study part I and II:
- Subjects with a history of atopy or respiratory disease, as indicated by the ISAAC questionnaire.
- Study part III:
- Mental retardation
- active smoking
- heart disease
- syndromes
- congenital malformations of the airways
- inability to perform the measurements
- for patients with lower respiratory tract infection: oxygen need, asthma or other chronic lung disease, active or passive smoking, inability to perform the measurements.
Key Trial Info
Start Date :
February 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
255 Patients enrolled
Trial Details
Trial ID
NCT00983671
Start Date
February 1 2010
End Date
December 1 2013
Last Update
July 22 2011
Active Locations (1)
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1
Maastricht University Medical Centre, Pediatric Pulmonology
Maastricht, Po Box 5800, Netherlands, 6202 AZ