Status:
COMPLETED
Conjunctival Allergen Challenge (CAC) Following Allergen Exposure in the Allergen BioCube (ABC)
Lead Sponsor:
ORA, Inc.
Conditions:
Allergic Rhinoconjunctivitis
Eligibility:
All Genders
18+ years
Brief Summary
To evaluate the effect of Conjunctival Allergen Challenge (CAC) with Dust Mites on nasal and ocular allergic symptoms following allergen exposure in the Allergen BioCube (ABC).
Eligibility Criteria
Inclusion
- be at least 18 years of age;
- if female, cannot be pregnant or nursing;
- have a history of ocular and nasal allergy;
- have a positive skin test reaction to ragweed within the past 24 months;
- may/may not have a positive skin test reaction to dust mites within the past 24 months
Exclusion
- have a history of mild persistent, moderate or severe asthma within the preceding 5 years according to the National Heart, Blood and Lung Institute classification;
- have a compromised lung function;
- have any ocular condition that could affect the subject's health or the study parameters;
- have any presence of active ocular or sinus infection;
- have significant nasal conditions;
- have any significant illness that could be expected to interfere with the subject's health or with the study parameters;
- use specified disallowed medications (topical, topical ophthalmic, systemic and/or injectable treatments and all anti-allergy therapies) during the study or appropriate pre-study washout period;
- have used an investigational drug or device within 30 days of starting the study or be concurrently enrolled in another investigational drug or device study within 30 days of the study;
Key Trial Info
Start Date :
September 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2010
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00985296
Start Date
September 1 2009
End Date
August 1 2010
Last Update
September 21 2010
Active Locations (1)
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1
ORA, Inc.
Andover, Massachusetts, United States, 01810