Status:
COMPLETED
Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome
Lead Sponsor:
University of California, San Diego
Conditions:
Polycystic Ovary Syndrome
Eligibility:
FEMALE
18-37 years
Phase:
NA
Brief Summary
Jeffrey Chang MD is conducting a research study to learn more about the increased male hormone levels, otherwise known as androgens, seen in women with polycystic ovary syndrome (PCOS). Women with PCO...
Detailed Description
The first part of this study looks specifically at the structure of the ovaries, which are the female sex glands where both androgens and estrogens (female hormones) are made. It involves imaging your...
Eligibility Criteria
Inclusion
- A group of 40 women with PCOS and 20 normal women ages 18-37 will be studied.
- Subjects will be determined to have PCOS based on clinical history of irregular menses and clinical or laboratory evidence of hyperandrogenism and polycystic ovaries on ultrasound.
- Subjects should not have been on any hormonal therapy or metformin for at least 2 months prior to study start.
- Subjects will be determined to be normal controls if they have a clinical history of regular periods
Exclusion
- Women with hemoglobin less than 11 gm/dl at screening evaluation
- Women with untreated thyroid abnormalities
- Pregnant women or women who are nursing
- Women with BMI \> 37
- Women with known sensitivity to the agents being used
- Women with prosthetic devices (i.e.,ear)/ shunts (ventricular), Hearing aids, Metal plate/pins/screws/wires
- Women with diabetes, or renal, liver, or heart disease.
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT00989781
Start Date
September 1 2009
End Date
September 1 2013
Last Update
June 4 2018
Active Locations (1)
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1
UCSD Medical Center
San Diego, California, United States, 92103