Status:
COMPLETED
Rule Out Myocardial Infarction by Computer Assisted Tomography
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Acute Coronary Syndrome
Myocardial Infarction
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acu...
Eligibility Criteria
Inclusion
- Patients with any episode \> five minutes of chest pain being admitted to rule out acute coronary syndrome
Exclusion
- Positive initial troponin or CK-MB tests
- Diagnostic ECG changes (ST- segment elevation or horizontal ST- segment depression in more than two contiguous leads)
- Unstable clinical condition (hemodynamically unstable, ventricular tachycardia, persistent chest pain despite adequate therapy)
- Creatinine Clearance \<50 mL/min
- Known allergy to iodinated contrast agents
- Patients on metformin therapy unable or unwilling to discontinue therapy for 48 hours after CT scan procedure
- Known asthma, reactive airway disease
- Patients currently in atrial fibrillation
- Previous intolerance to beta blocker
- Patients that are referred for coronary angiography/PCI by their PCP or cardiologist.
Key Trial Info
Start Date :
May 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2009
Estimated Enrollment :
368 Patients enrolled
Trial Details
Trial ID
NCT00990262
Start Date
May 1 2005
End Date
April 1 2009
Last Update
October 6 2009
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114