Status:

COMPLETED

Growth Factor/Insulin-like Growth Factor (GH/IGF)-1 Axis in Obese Subjects in Treatment With Orlistat

Lead Sponsor:

Federico II University

Conditions:

Obesity

Eligibility:

FEMALE

45-65 years

Brief Summary

The beneficial effects on plasma lipids of Orlistat, a selective gastrointestinal lipase inhibitor, are largely independent of weight loss, and might include differential effects plasma non-esterified...

Detailed Description

Subjects: Twenty obese postmenopausal women (age: 53.6±6.2; BMI: 34.1±4.0. Subjects were recruited, evaluated, and monitored at the Endocrinology Unit of the Department of Molecular and Clinical Endo...

Eligibility Criteria

Inclusion

  • women
  • post-menopausal age
  • class I-II obesity
  • normal thyroid, liver, and kidney function

Exclusion

  • type 2 diabetes mellitus
  • use of hypolipaemic agents

Key Trial Info

Start Date :

December 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 1 2009

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00991926

Start Date

December 1 2006

End Date

February 1 2009

Last Update

October 14 2009

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