Status:

COMPLETED

Oral Titrated Misoprostol for Induction of Labour

Lead Sponsor:

Instituto Materno Infantil Prof. Fernando Figueira

Collaborating Sponsors:

Instituto de Saúde Elpidio de Almeida

Universidade Federal do Ceara

Conditions:

Labor, Induced

Eligibility:

FEMALE

18-50 years

Phase:

NA

Brief Summary

The purpose of this study is to compare effectiveness and safety of an oral titrated solution of misoprostol with vaginal misoprostol for induction of labour with an alive fetus.

Detailed Description

Several methods for induction of labour are available. However, the most effective and with less frequency of adverse effects is still unknown. Vaginal misoprostol has been used frequently to induce l...

Eligibility Criteria

Inclusion

  • Indication for labour induction
  • Term pregnancy with alive fetus
  • Bishop score less than six

Exclusion

  • Age less than 18 years
  • Previous uterine scar
  • Nonvertex presentation
  • Non-reassuring fetal status
  • Fetal anomalies
  • Fetal growth restriction
  • Genital bleeding
  • Tumors, malformations and/or ulcers of vulva, perineum or vagina

Key Trial Info

Start Date :

November 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2011

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00992524

Start Date

November 1 2009

End Date

June 1 2011

Last Update

June 23 2011

Active Locations (1)

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Instituto de Medicina Integral Professor Fernando Figueira (IMIP)

Recife, Pernambuco, Brazil, 50070-550