Status:

COMPLETED

Effect of GLP-1 on Insulin-dose, Risk of Hypoglycemia and Gastric Emptying Rate in Patients With Type 1 Diabetes

Lead Sponsor:

Hvidovre University Hospital

Conditions:

Diabetes Mellitus

Eligibility:

All Genders

18-50 years

Phase:

PHASE2

PHASE3

Brief Summary

The aim of the study is to investigate the effect of Victoza (a GLP-1 receptor agonist)on insulin-dose, risk of hypoglycemia and gastric emptying rate during hypoglycemia in patients with type 1 diabe...

Eligibility Criteria

Inclusion

  • age 18-50y,
  • BMI 18-27,
  • caucasian origin,
  • type 1 diabetes diagnosed between age 5 and age 40,
  • no known diabetes complications or cardiovascular diseases,
  • no medication known to influence glucose homeostasis,
  • no pregnancy

Exclusion

  • diabetes complications,
  • autonomous nerve dysfunction,
  • anaemia,
  • HbA1c \< 8.5% at screening,
  • estimated by the investigator to be incapable of completing the trial.

Key Trial Info

Start Date :

October 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00993720

Start Date

October 1 2009

End Date

October 1 2010

Last Update

January 21 2011

Active Locations (1)

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1

Hvidovre University Hospital

Hvidovre, Denmark, 2650

Effect of GLP-1 on Insulin-dose, Risk of Hypoglycemia and Gastric Emptying Rate in Patients With Type 1 Diabetes | DecenTrialz