Status:
COMPLETED
Effect of Alpha Lipoic Acid on Obesity Related Comorbidities
Lead Sponsor:
Augusta University
Collaborating Sponsors:
Xinjiang Medical University
Conditions:
Obesity
Cardiovascular Disease
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
PHASE3
Brief Summary
The major objective of this study is to conduct a double-blind, placebo-controlled, randomized clinical trial to assess whether oral alpha lipoic acid supplementation will decrease cardiovascular dise...
Eligibility Criteria
Inclusion
- Han ethnicity
- BMI≥25kg/m2
- Having at least one of the following risk factors: borderline hypertension (130mmHg≤SBP\<140mmHg or 85mmHg≤DBP\<90mmHg), dyslipidemia (fasting total cholesterol ≥240mg/dl or HDL-C\<40mg/dl), or impaired fasting glucose (fasting glucose levels between 6.1 and 7.0mmol/L)
- 18-60 years old
- Not on any antioxidant vitamin supplement
Exclusion
- Pregnancy, lactation or child-bearing age without birth control device
- History of hypertension, diabetes, coronary heart disease(CHD), cancer or liver disease
- Anything that would impede the subject from complying with the ALA treatment
- History of psychiatric problems
Key Trial Info
Start Date :
July 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2010
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT00994513
Start Date
July 1 2009
End Date
May 1 2010
Last Update
September 24 2010
Active Locations (1)
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1
Xinjiang Medical University
Ürümqi, Xinjiang, China, 830054