Status:
COMPLETED
Cotinine Metabolism in Infants and Children
Lead Sponsor:
University of California, San Francisco
Conditions:
Secondhand Smoke Exposure
Eligibility:
All Genders
2-72 years
Phase:
PHASE1
Brief Summary
Levels of cotinine, a biomarker for nicotine, have been found to be higher in infants and small children than adults. This pharmacokinetic study is designed to determine whether children metabolize co...
Detailed Description
The long-term goal is to characterize developmental changes in CYP2A6 activity and nicotine and cotinine metabolism in infants and children. Our hypotheses are: * The rate of nicotine and cotinine me...
Eligibility Criteria
Inclusion
- Ages: 12 months, 13-24 months, and 25-83 months
- Caucasian (including Hispanic) and African American only
- Some exposure to secondhand smoke
Exclusion
- Any medical problems
- Taking prescription medication (there are exceptions)
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT00994591
Start Date
January 1 2007
End Date
June 1 2011
Last Update
May 24 2013
Active Locations (1)
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1
University of California, San Francisco, SFGH, CTSI,CRC
San Francisco, California, United States, 94101