Status:
COMPLETED
Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate
Lead Sponsor:
Pennington Biomedical Research Center
Collaborating Sponsors:
Ajinomoto USA, INC.
Conditions:
Obesity
Weight
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
A 4 week intake of drug to find a natural substance that may modify energy balance and may enhance health in combination with lifestyle changes with possible decrease in body weight.
Detailed Description
This study is a double-blind, placebo-controlled, single center, randomized, parallel arm clinical trial to test the impact of Dihydrocapsiate (placebo, 3 and 9 mg/d) ingested for 4 weeks on resting m...
Eligibility Criteria
Inclusion
- Men between 20-60 years old
- Healthy as assessed by medical history and standard medical exam
- Weight-stable
- Body mass index of 25 to 34.9 kg/m2
- Non-smoker
- Sedentary lifestyle: not being physically active grater than 3 days/week for 20 min each time for the previous 6 months, and not participating in regular resistance exercise.
Exclusion
- Subjects enrolled in a diet to increase or decrease body weight
- Special diet or food aversiions to common foods
- Has allergy to chilli pepper
- Eating chilli peppers on a daily basis
- Usually consuming more than 2 cups of tea or coffee/day
- Usually consuming more than 4 cans of caffeinated soft drinks a day
- Usually consuming more than 3 standard alcohol drinks/day
- Regular use of medications (weight loss drugs, drugs affecting energy metabolism, drugs for depression)
- Usual intake of illicit substances
- Claustrophobia
- Participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT00999297
Start Date
July 1 2008
End Date
December 1 2014
Last Update
November 20 2015
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70809