Status:
COMPLETED
Neuropsychologic, Neuroradiologic, Endocrinologic, and Genetic Aspects of Klinefelter Syndrome
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
Aarhus University Hospital
Conditions:
Klinefelter Syndrome
Eligibility:
All Genders
18-60 years
Brief Summary
The purpose of this study is to investigate the following: 1. Whether Klinefelter Syndrome is associated with altered total and regional brain volumes and altered brain activity. 2. The influence of ...
Detailed Description
Klinefelter syndrome (KS) is the most common sex-chromosome disorder in men with a prevalence of 1 in 660 men. Men with the syndrome have an additional X-chromosome. The syndrome is associated with co...
Eligibility Criteria
Inclusion
- age between 18 and 60 years
- verified KS karyotype (KS patients)
Exclusion
- present or past neurological diseases
- present or past head trauma
- contraindication to perform MR scans(Claustrophobia,Magnetic or electric foreign bodies - including cardiac pacemakers, magnetic cerebrovascular clips and electric non-removable appliances dosing medicine)
- extreme adiposity (BMI \> 35 kg/m2)
Key Trial Info
Start Date :
November 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
146 Patients enrolled
Trial Details
Trial ID
NCT00999310
Start Date
November 1 2009
End Date
June 1 2013
Last Update
June 2 2015
Active Locations (1)
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1
Medical Department M, Endocrinology and Diabetes, and Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44
Aarhus, Denmark, 8000