Status:

COMPLETED

In Vivo Evaluation of the Physiological Effects of Arabinoxylan-oligosaccharides (AXOS) in Healthy Subjects (Juniors)

Lead Sponsor:

Fugeia NV

Conditions:

Gastrointestinal Health

Healthy Subjects

Eligibility:

All Genders

8-12 years

Phase:

NA

Brief Summary

The investigational product used in this study is a soft drink containing an arabinoxylan-oligosaccharide (AXOS) preparation extracted from wheat bran (hereafter called Wheat Bran Extract, WBE). The ...

Eligibility Criteria

Inclusion

  • regular eating habits
  • consent to take in the study product according to the study protocol
  • consent of parents for follow-up of the protocol
  • subject is willing to maintain his/her habitual food and beverage intake throughout the study period (with the exception of omission of prebiotic and probiotic food products as indicated in the study protocol)

Exclusion

  • low-calorie diet or other extreme dietary habits in the 6 weeks before the start of the clinical trial
  • recent use of antibiotics
  • abdominal surgery in the past
  • use of medication or dietary supplements known to influence gastrointestinal tract within two weeks of start of clinical trial. Examples of such medication/dietary supplements are antispasmodics, anti-diarrhea medication and/or probiotic medication
  • serious illness within 3 months of start of clinical trial
  • chronic gastrointestinal conditions such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), chronic constipation, history of frequent diarrhea, clinically important lactose intolerance
  • complete anesthetics within 3 month of the start of the clinical trial
  • allergy for wheat products
  • celiac disease
  • Subject has a condition the Investigator believes would interfere with his or her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results or put the subject at undue risk

Key Trial Info

Start Date :

March 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2009

Estimated Enrollment :

29 Patients enrolled

Trial Details

Trial ID

NCT01001949

Start Date

March 1 2009

End Date

October 1 2009

Last Update

October 27 2009

Active Locations (1)

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1

Department of Gastrointestinal Research, Laboratory Digestion and Absorption

Leuven, Belgium, 3000