Status:
COMPLETED
Short Term Effects and Risks of Physical Exercise in Subjects With Hypohidrotic Ectodermal Dysplasia
Lead Sponsor:
University Hospital Erlangen
Collaborating Sponsors:
Pervormance GmbH
Conditions:
X-Linked Hypohidrotic Ectodermal Dysplasia
Exercise-induced Rise of Body Temperature
Eligibility:
MALE
7-18 years
Brief Summary
Because of their lack of sweat glands individuals with hypohidrotic ectodermal dysplasia (HED) are at particular risk of life-threatening hyperthermia during exercise in a warm environment. In this st...
Eligibility Criteria
Inclusion
- for patients: hypohidrotic ectodermal dysplasia caused by EDA gene mutations
- regular fluid intake prior to the investigation
- written informed consent
Exclusion
- acute febrile illness
- acute or chronic heart disease
- arterial hypertension
- gastrointestinal disorders
- implantable electronic devices
- MRI investigation scheduled for the 5 days subsequent to the study
- clinical signs or diagnostic findings of dehydration
Key Trial Info
Start Date :
April 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT01135888
Start Date
April 1 2009
End Date
February 1 2010
Last Update
August 19 2021
Active Locations (1)
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1
University Hospital Erlangen
Erlangen, Bavaria, Germany, 91054