Status:

WITHDRAWN

Assessment of the Sympathetic Nervous System Blockade of the Upper Limb After a Brachial Plexus Block in Patients With End Stage Renal Failure

Lead Sponsor:

University of Nottingham

Conditions:

Renal Failure

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to investigate what effect a local anesthetic nerve block of the arm in patients with end stage renal failure has upon blood flow in the skin of the arm.

Detailed Description

Aim To quantify the degree of sympathetic blockade in the upper limb in patients with end stage renal failure produced during a regional anaesthetic technique, using laser Doppler flowmetry. Hypothe...

Eligibility Criteria

Inclusion

  • Patients with end stage renal failure
  • Over 18 years of age
  • Written consent obtained
  • Due to undergo surgery for forearm fistula creation under a regional block

Exclusion

  • Smokers
  • Damaged skin on the arm
  • Circulatory disorders such as Raynaud's disease, systemic sclerosis, sickle cell trait or disease
  • Current use of beta blockers
  • undergoing haemodialysis for more than 12 months

Key Trial Info

Start Date :

February 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT01135979

Start Date

February 1 2010

End Date

December 1 2012

Last Update

March 6 2013

Active Locations (1)

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1

Nottingham University Hospitals NHS Trust

Nottingham, Nottinghamshire, United Kingdom, NG7 2UH