Status:
COMPLETED
A Study to Evaluate the Effect of Mechanical Ventilation on the Inferior Vena Cava Collapsibility Index
Lead Sponsor:
Naeem Ali, MD
Conditions:
Respiratory Failure
Eligibility:
All Genders
18-99 years
Brief Summary
Previous research has shown that the Inferior Vena Cava Collapsibility Index (IVCCI) can be used to assess volume status. One limitation of the previous work is that changes in intra-thoracic pressure...
Detailed Description
Initially eligible patients will be those admitted to the OSU MICU and 8ICU within the prior 48 hours. These patients will be screened for predetermined exclusion criteria. Eligible patients will have...
Eligibility Criteria
Inclusion
- Age\>17 years
- Current use of mechanical ventilation through an endotracheal tube.
- Admitted to ICU within last 48 hours
Exclusion
- Severe COPD by history (documented FEV1\<50% predicted or CT evidence of emphysema)
- Current suspected Asthma Exacerbation
- Profound Hypoxia defined as a FiO2 requirement \>90% or a PEEP \>10 mmHg
- Patient-ventilator desynchrony or active agitation
- Unstable O2 requirement as determined by the primary clinical team.
- Prisoners
- Bedside clinician refusal (physician or treating nurse).
- Exclusion Criteria for ventilator changes:
- Cardiovascular instability (any increase in rate of vasopressors or i.v. fluid bolus for hypotension within the last four hours)
- Current PEEP requirements of \>15cmH2O
- Current SpO2 of \<88%.
Key Trial Info
Start Date :
October 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT01136109
Start Date
October 1 2009
End Date
February 1 2013
Last Update
March 5 2024
Active Locations (1)
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1
The Ohio State University
Columbus, Ohio, United States, 43221