Status:
UNKNOWN
Clinical, Histological and Biochemical Characterization of Hyperpigmented Lesion
Lead Sponsor:
National University Hospital, Singapore
Conditions:
Lentigo
Melasma
Eligibility:
All Genders
21-80 years
Brief Summary
Hypothesis - The developments of solar lentigine and melasma are due to mutations in keratinocytes that drive the production and transfer of pigment from melanocytes to keratinocytes.
Detailed Description
Aims - 1. Characterize and classify lentigines and mealsma from a clinical and physiological point of view. This will help us to better understand the cellular processes leading to the development of...
Eligibility Criteria
Inclusion
- Solar Lentigines and/or Melasma on facial, or neck areas
- Ethnic background: Chinese, Malay, Indian, Caucasian
- Age 21 - 80 years old
- Ability to provide informed consent
Exclusion
- Pregnant and lactating women
- Children under the age of 20
- Neoplasm (past or present) in excised area
- Patients with communicable disease
- Immuno-compromised patients
- Current treatment with an investigational drug
Key Trial Info
Start Date :
June 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2015
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT01136629
Start Date
June 1 2008
End Date
May 1 2015
Last Update
January 28 2014
Active Locations (1)
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1
National University Hospital, Singapore
Singapore, Singapore, Singapore, 119074