Status:
COMPLETED
Efficacy of Proton Pump Inhibitor in Prevention of Clopidogrel-related Peptic Ulcer
Lead Sponsor:
Kaohsiung Veterans General Hospital.
Conditions:
Peptic Ulcer
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
Proton Pump Inhibitors (PPI) can prevent the recurrence of peptic ulcer in clopidogrel users.
Detailed Description
The aim of the prospective, randomized study is to investigate the efficacy of PPI in prevention of ulcer recurrence for clopidogrel users. We plan to enroll 300 clopidogrel users without baseline gas...
Eligibility Criteria
Inclusion
- We plan to enroll 300 clopidogrel users without baseline gastroduodenal ulcer at initial endoscopy. The patients will be randomly assigned to receive either (1) esomeprazole (20 mg qd) plus clopidogrel or (2) clopidogrel treatment alone for 6 months.
Exclusion
- serious disease 2.refuse informed consent
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
165 Patients enrolled
Trial Details
Trial ID
NCT01138969
Start Date
August 1 2008
End Date
December 1 2012
Last Update
September 9 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan, 813