Status:
UNKNOWN
The Contribution of Lp-PLA2 Level to the Presence of Coronary Plaques in Patients With Non Alcoholic Fatty Liver Disease
Lead Sponsor:
Ziv Hospital
Conditions:
Nonalcoholic Fatty Liver Disease
Coronary Artery Disease
Eligibility:
All Genders
18+ years
Brief Summary
The most common cause of death in patients with NAFLD(Nonalcoholic Fatty Liver Disease) is CAD(Coronary Artery Disease). NAFLD patients have 65% more mortality than general population. The aim of the ...
Detailed Description
Background: The most common cause of death in patients with NAFLD(Nonalcoholic Fatty Liver Disease) is CAD(Coronary Artery Disease). NAFLD patients have 65% more mortality than general population. The...
Eligibility Criteria
Inclusion
- Patients at intermediate risk for significant CAD was admitted to the hospital with the diagnosis of chest pain or undergoing elective CT coronarography due to suspection of coronary artery disease.
- Male and female 18years or older.
- Able to provide written informed consent.
- Intermediate Risk patients for having significant CAD is defined as:
- chest pain or dyspnea in the presence of negative stress tests;
- the absence of chest pain but positive stress tests;
- the absence of chest pain and of positive stress tests but intermittent arrhythmias
Exclusion
- Acute coronary syndrome presentation:
- ST segment deviation on ECG and/or
- Cardiac troponin elevation.
- Chest pain in combination with positive tests for myocardial ischemia
- Hemodynamic instability on presentation.
- Inability to write inform consent.
- Age \<18 years.
- Participation in an investigational study within the previous 30days.
Key Trial Info
Start Date :
July 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2011
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01139632
Start Date
July 1 2010
End Date
March 1 2011
Last Update
April 6 2011
Active Locations (1)
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1
Ziv medical center liver unit
Safed, Israel, Israel, 13100